Methanedriol dipropionate (M.D.) is a form of water-soluble methanedriol, but methanedriol dipropionate remains effective over a long period of time. On the one hand, methanedriol dipropionate can be dissolved in oil for injections and, on the other hand, methanedriol dipropionate can be produced in tablet form, since it has a strong anabolic and androgenic component even with oral administration of MD, making it suitable for building strength and muscle mass. The effect can be compared to a cross between Deca-Durabolin and Testosterone-Enanthate. Like testosterone, it contributes to a gain in strength and muscles, but does not retain more water than Deca-Durabolin. However, the best results can be obtained when M.D. is taken not alone but in combination with another steroid. This is because M.D. is able to magnify the effects of other steroid compounds. This happens through increasing sensitization of the androgenic receptors of the muscle cell, whereby a higher amount of the steroid molecules of the additionally ingested steroids can be absorbed by the receptors. This also explains why the injectable M.D. only exists today as a combination compound with an additional steroid substance. Injectable M.D. is only available in the Australian veterinary steroids Drive, Spectriol, Geldabol, and Filibol Forte so the compound is difficult to source. The few athletes using this drug report good strength, solid muscle gain, and low water retention. The combination heroids aromatize only slightly, so if they are only M.D. the use of antiestrogens may be appropriate. The injectable form is only slightly toxic.

The usual dosage for athletes is 100 mg every 2-3 days. In Europe only the oral form of M.D. available. In this case, too, it is advantageous to combine M.D. with another steroid, preferably an injectable one. The normal daily dose is 40-60 mg and is usually divided into 2-3 single doses over the day. The tablets are usually only taken for 4-6 weeks, as the effect diminishes quickly and thus requires higher dosages. They are also I 7-alpha-alkylated, so even a low dose age and a short intake can be harmful to the liver. Because of their androgenic effects women rarely use PD. Possible side effects of the tablet form can include increased levels of liver toxins, gastrointestinal pain, acne, gynecomastia, increased aggressiveness and high blood pressure.