Dutahair
- 17,85€
- Net € 17.85
- AvailabilityIn stock
- Manufacturer Fortune
- Article no. 669
- Package: 0.5 mg (15 capsules)
- Stoff: Dutasterid (Avodart)
Dutasteride (Avodart) is an androgen inhibitor medication. Dutasteride is mainly used as a treatment for male pattern baldness and enlarged prostate. Dutasteride is not routinely used in the treatment of acne.
Dutasteride is usually in oral formulations, but topical Dutasteride may be better for use as an acne treatment. Dutasteride is easily absorbed into the skin, and applied topically Dutasteride is expected to have significantly fewer side effects than oral Dutasteride. Topical dutasteride solutions may be available in certain regions.
Dutasteride inhibits the synthesis of the powerful androgen (male hormone), DHT. DHT is closely related to testosterone but is more powerful. Inhibiting the effects of androgen hormones can help improve acne symptoms in some individuals by slowing the growth of the sebum glands. In people with androgen-induced acne, high levels of androgen hormones cause increased sebum activity, which leads to increased sebum production, clogged pores, and overgrowth of acne-causing P. acnes bacteria within follicles.
Dutasteride works by blocking the activity of an enzyme called 5-aplha reductase that converts testosterone to dihydrotestosterone (DHT). There are two different versions of the 5-alpha reductase enzyme in humans. Finasteride is an androgen inhibitor that is closely related to Dutasteride. Dutasteride is a stronger inhibitor of DHT synthesis than finasteride because it inhibits both forms of the enzyme, while finasteride only inhibits one.
Androgen hormones are an integral part of male biology. Because androgen inhibitors have significant side effects when used in men, they are typically only used to treat acne in women. However, Dutasteride is one of the few androgen inhibitors that is routinely used in men. Two of the most common side effects of androgen inhibitor use in men are a reduced sex drive and decreased muscle mass.